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Hemodynamic variables and <t>ECG</t> parameters in UUO. ( A – D ): MAP ( A ), MAP response to L-NAME administration ( B ), HR ( C ), and RR-interval duration ( D ) in the three groups of mice. ( E ): Fragments of representative ECG recordings showing QRS prolongation in 28UUO group compared to the Int group. ( F , G ): durations of QRS complex and QT-interval in the three groups of mice. Number of mice per group: Int—8; 14UUO—8; 28UUO—7. * p < 0.05—statistically significant difference compared to the Int group (one-way ANOVA, Dunnett’s post hoc test).
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Figure 2. Retigabine reduces the incidence of spontaneous VAs following AMI. A, Representative <t>ECG</t> traces (lead II) after coronary ligation. B, Comparison of Tp-Te (n=12). C–E, Frequency of VPB and frequency and duration of VT (n=12). F, Incidence of VF (n=12). Values represent the mean±SEM. All measurements were obtained within the first hour post coronary artery ligation. AMI indicates acute myocardial ischemia; Tp-Te, Tpeak-Tend interval; VF, ventricular fibrillation; VPB, ventricular premature beats; and VT, ventricular tachycardia.
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Figure 2. Retigabine reduces the incidence of spontaneous VAs following AMI. A, Representative <t>ECG</t> traces (lead II) after coronary ligation. B, Comparison of Tp-Te (n=12). C–E, Frequency of VPB and frequency and duration of VT (n=12). F, Incidence of VF (n=12). Values represent the mean±SEM. All measurements were obtained within the first hour post coronary artery ligation. AMI indicates acute myocardial ischemia; Tp-Te, Tpeak-Tend interval; VF, ventricular fibrillation; VPB, ventricular premature beats; and VT, ventricular tachycardia.
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Hemodynamic variables and ECG parameters in UUO. ( A – D ): MAP ( A ), MAP response to L-NAME administration ( B ), HR ( C ), and RR-interval duration ( D ) in the three groups of mice. ( E ): Fragments of representative ECG recordings showing QRS prolongation in 28UUO group compared to the Int group. ( F , G ): durations of QRS complex and QT-interval in the three groups of mice. Number of mice per group: Int—8; 14UUO—8; 28UUO—7. * p < 0.05—statistically significant difference compared to the Int group (one-way ANOVA, Dunnett’s post hoc test).

Journal: International Journal of Molecular Sciences

Article Title: Adaptive and Pathological Changes of the Cardiac Muscle in a Mouse Model of Renocardiac Syndrome: The Role of Nestin-Positive Cells

doi: 10.3390/ijms26168100

Figure Lengend Snippet: Hemodynamic variables and ECG parameters in UUO. ( A – D ): MAP ( A ), MAP response to L-NAME administration ( B ), HR ( C ), and RR-interval duration ( D ) in the three groups of mice. ( E ): Fragments of representative ECG recordings showing QRS prolongation in 28UUO group compared to the Int group. ( F , G ): durations of QRS complex and QT-interval in the three groups of mice. Number of mice per group: Int—8; 14UUO—8; 28UUO—7. * p < 0.05—statistically significant difference compared to the Int group (one-way ANOVA, Dunnett’s post hoc test).

Article Snippet: The last 5 min interval of ECG recording was exported to a binary file and then imported into LabChart 7.3.4 with ECG Analysis Module 2.3.2 (ADInstruments, Dunedin, New Zealand).

Techniques:

Figure 2. Retigabine reduces the incidence of spontaneous VAs following AMI. A, Representative ECG traces (lead II) after coronary ligation. B, Comparison of Tp-Te (n=12). C–E, Frequency of VPB and frequency and duration of VT (n=12). F, Incidence of VF (n=12). Values represent the mean±SEM. All measurements were obtained within the first hour post coronary artery ligation. AMI indicates acute myocardial ischemia; Tp-Te, Tpeak-Tend interval; VF, ventricular fibrillation; VPB, ventricular premature beats; and VT, ventricular tachycardia.

Journal: Journal of the American Heart Association

Article Title: Targeted M‐Channel Activation in the Left Stellate Ganglion Protects Against Ischemia‐Induced Ventricular Arrhythmias in Canines

doi: 10.1161/jaha.124.039059

Figure Lengend Snippet: Figure 2. Retigabine reduces the incidence of spontaneous VAs following AMI. A, Representative ECG traces (lead II) after coronary ligation. B, Comparison of Tp-Te (n=12). C–E, Frequency of VPB and frequency and duration of VT (n=12). F, Incidence of VF (n=12). Values represent the mean±SEM. All measurements were obtained within the first hour post coronary artery ligation. AMI indicates acute myocardial ischemia; Tp-Te, Tpeak-Tend interval; VF, ventricular fibrillation; VPB, ventricular premature beats; and VT, ventricular tachycardia.

Article Snippet: The Tpeak- Tend (Tp- Te) interval was measured 1 hour post AMI using LabChart 8.1 software with ECG Analysis Module v2.4 (AD Instruments).

Techniques: Ligation, Comparison